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Protocol NU MC12M02

Title Feasibility and Safety of Minimally Invasive Inguinal Lymph Node Dissection in Patients with Melanoma
Purpose The purpose of this research is to study the safety of a new minimally invasive technique to remove the lymph nodes in your groin.
Overview This study is for patients who have a melanoma which has spread to the groin and it is advised that they have a groin dissection. A minimally invasive lymph node dissection is a new way to remove and examine inguinal lymph nodes. Very little data exists on the safety of the procedure. It is unknown if the risks of this procedure are equal to, worse or better than those from the standard open approach. Because this is a less invasive approach, we anticipate it will have a safer risk profile when compared to the current standard of care.
Who May
be Eligible
Some of the eligibility criteria include:
  • Participants in this study must be at least 18 years old.
  • Participants must have malignant melanoma in the inguinal (groin) area requiring requiring surgery, and surgery is planned.
Note: This is only a partial list of eligibility criteria. Please contact the Robert H. Lurie Comprehensive Cancer Center of Northwestern University for complete screening information if you are interested in this clinical trial.

Description of Treatment Participants who take part in this study are scheduled to have surgery to remove lymph nodes in one or both groins to look for evidence of melanoma. Traditionally this requires a 6 to 10 inch incision in the groin to remove all the lymph nodes. This study involves making 3 small (1/2 inch) incisions and removing all the lymph nodes in the groin using cameras and special laparoscopic instruments. The lymph nodes removed during the operation will be examined by a specially-trained physician to look for evidence of melanoma just as it would happen if the procedure was done through a traditional open technique. After surgery, participants will need to be seen by their surgeon, as is standard after an operative procedure.

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If you have questions about current or future trials, contact the Cancer Center at 866-LURIE-CC (866-587-4322) or
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